{"id":84346,"date":"2020-05-25T03:35:20","date_gmt":"2020-05-25T06:35:20","guid":{"rendered":"https:\/\/iclos.global\/eng\/?post_type=product&p=84346"},"modified":"2021-04-21T20:11:18","modified_gmt":"2021-04-21T23:11:18","slug":"tuzdal","status":"publish","type":"product","link":"https:\/\/iclos.global\/eng\/producto\/tuzdal\/","title":{"rendered":"Tuzdal"},"content":{"rendered":"

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Principio activo: Trastuzumab
\nPresentaciones: 440mg x vial liofilizado<\/h3>\n

 <\/p>\n

<\/h4>\n

Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos)<\/strong><\/p>\n

Trastuzumab es un anticuerpo monoclonal recombinante humano IgG que reconoce el
\nreceptor Her2 presente en ciertos tipos tumorales. Al unirse al receptor desencadena la
\ninterrupci\u00f3n del ciclo celular y la muerte celular programada. Adem\u00e1s, promueve la muerte
\ncelular a trav\u00e9s del sistema inmune (mediante las c\u00e9lulas Natural Killer).[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=\u00bb0″ overlay_alpha=\u00bb50″ gutter_size=\u00bb3″ column_width_percent=\u00bb100″ shift_y=\u00bb0″ z_index=\u00bb0″ el_class=\u00bbcatalogo-item\u00bb][vc_column width=\u00bb1\/1″][vc_row_inner][vc_column_inner width=\u00bb1\/1″][vc_empty_space empty_h=\u00bb0″][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=\u00bb5\/6″][vc_column_text][\/vc_column_text][\/vc_column_inner][vc_column_inner width=\u00bb1\/6″][vc_column_text]\"\"[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Principio activo: Trastuzumab
\nPresentaciones: 440mg x vial liofilizado<\/h3>\n

 <\/p>\n

<\/h4>\n

Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos)<\/strong><\/p>\n

Trastuzumab es un anticuerpo monoclonal recombinante humano IgG que reconoce el receptor Her2 presente en ciertos tipos tumorales. Al unirse al receptor desencadena la interrupci\u00f3n del ciclo celular y la muerte celular programada. Adem\u00e1s, promueve la muerte celular a trav\u00e9s del sistema inmune (mediante las c\u00e9lulas Natural Killer).<\/p>\n

Indicaciones terap\u00e9uticas<\/strong><\/p>\n

    \n
  • C\u00e1ncer de mama Her2+ en estadios tempranos.<\/li>\n
  • C\u00e1ncer de mama Her2+ metast\u00e1sico.<\/li>\n
  • C\u00e1ncer g\u00e1strico metast\u00e1sico Her2+.<\/li>\n<\/ul>\n

    Aprobaciones y pautas (FDA; EMA; ASCO; ESMO)<\/strong><\/p>\n

    Trastuzumab ha sido aprobado por EMA y FDA para las indicaciones
    \nanteriormente mencionadas.<\/p>\n

    Dosis y plan terap\u00e9utico<\/strong><\/p>\n

    El plan terap\u00e9utico var\u00eda seg\u00fan la indicaci\u00f3n. La dosis inicial para c\u00e1ncer de mama (precoz o metast\u00e1sico) es de 4mg\/kg por v\u00eda IV, y para c\u00e1ncer g\u00e1strico metast\u00e1sico es de 8mg\/kg v\u00eda IV. Las dosis de mantenimiento var\u00edan entre 2 \u2013 8 mg\/kg con frecuencia semanal o cada 21 d\u00edas seg\u00fan indicaci\u00f3n.<\/p>\n

    Por m\u00e1s informaci\u00f3n ver la ficha t\u00e9cnica del producto.<\/em><\/p>\n","protected":false},"featured_media":85427,"template":"","meta":[],"product_cat":[125],"product_tag":[],"class_list":{"0":"post-84346","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sin-categorizar","7":"pa_area-terapeutica-biotecnologicos","8":"pa_area-terapeutica-oncologia","9":"pa_nombre-tuzdal","10":"pa_principio-activo-trastuzumab","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"yoast_head":"\nTuzdal - ICLOS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/iclos.global\/eng\/producto\/tuzdal\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tuzdal - ICLOS\" \/>\n<meta property=\"og:description\" content=\"Principio activo: Trastuzumab Presentaciones: 440mg x vial liofilizado   Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos) Trastuzumab es un anticuerpo monoclonal recombinante humano IgG que reconoce el receptor Her2 presente en ciertos tipos tumorales. 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