{"id":86110,"date":"2021-04-21T11:11:36","date_gmt":"2021-04-21T14:11:36","guid":{"rendered":"https:\/\/iclos.global\/eng\/?post_type=product&p=86110"},"modified":"2021-04-21T11:17:43","modified_gmt":"2021-04-21T14:17:43","slug":"inoxtar","status":"publish","type":"product","link":"https:\/\/iclos.global\/eng\/producto\/inoxtar\/","title":{"rendered":"Inoxtar"},"content":{"rendered":"

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Principio activo: Pazopanib
\nPresentaciones: 400 mg x 60 comprimidos
\n200mg x 90 comprimidos<\/h3>\n

 <\/p>\n

<\/h4>\n

Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos)<\/strong><\/p>\n

Pazopanib inhibidor multi-tirosin quinasa de: receptores VEGD 1, 2 y 3; receptores PDGF, receptor de citoquina cKit, receptor de IL-2 inducible por quinasa de c\u00e9lulas T (Itk). Su funci\u00f3n principal es intervenir con la angiog\u00e9nesis, impidiendo el crecimiento tumoral y su sobrevida.[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=\u00bb0″ overlay_alpha=\u00bb50″ gutter_size=\u00bb3″ column_width_percent=\u00bb100″ shift_y=\u00bb0″ z_index=\u00bb0″ el_class=\u00bbcatalogo-item\u00bb][vc_column width=\u00bb1\/1″][vc_row_inner][vc_column_inner width=\u00bb1\/1″][vc_empty_space empty_h=\u00bb0″][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=\u00bb5\/6″][vc_column_text][\/vc_column_text][\/vc_column_inner][vc_column_inner width=\u00bb1\/6″][vc_column_text]\"\"[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Principio activo: Pazopanib
\nPresentaciones: 400 mg x 60 comprimidos
\n200mg x 90 comprimidos<\/h3>\n

 <\/p>\n

<\/h4>\n

Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos)<\/strong><\/p>\n

Pazopanib inhibidor multi-tirosin quinasa de: receptores VEGD 1, 2 y 3; receptores PDGF, receptor de citoquina cKit, receptor de IL-2 inducible por quinasa de c\u00e9lulas T (Itk). Su funci\u00f3n principal es intervenir con la angiog\u00e9nesis, impidiendo el crecimiento tumoral y su sobrevida.<\/p>\n

Indicaciones terap\u00e9uticas<\/strong><\/p>\n

    \n
  • C\u00e1ncer de c\u00e9lulas renal avanzado.<\/li>\n
  • Ciertas formas de sarcoma tisular de tejidos blandos.<\/li>\n<\/ul>\n

    Aprobaciones y pautas (FDA; EMA; ASCO; ESMO)<\/strong><\/p>\n

    Paznopanib ha sido aprobado por EMA y FDA para las indicaciones anteriormente mencionadas.
    \nASCO y ESMO recomiendan el uso de Pazopanib como tratamiento de primera l\u00ednea para pacientes con c\u00e1ncer de las c\u00e9lulas renales.<\/p>\n

    Dosis y plan terap\u00e9utico<\/strong><\/p>\n

    El plan terap\u00e9utico var\u00eda seg\u00fan la indicaci\u00f3n. Se recomienda una dosis diaria m\u00e1xima de 800mg. La reducci\u00f3n inicial de dosis debe ser de 400mg. Aumentos o reducciones posteriores deben hacerse de a 200mg dependiendo de la tolerancia.<\/p>\n

    Por m\u00e1s informaci\u00f3n ver la ficha t\u00e9cnica del producto.<\/em><\/p>\n","protected":false},"featured_media":86111,"template":"","meta":[],"product_cat":[125],"product_tag":[],"class_list":{"0":"post-86110","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sin-categorizar","7":"pa_area-terapeutica-oncologia","8":"pa_nombre-inoxtar","9":"pa_principio-activo-pazopanib","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"yoast_head":"\nInoxtar - ICLOS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/iclos.global\/eng\/producto\/inoxtar\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inoxtar - ICLOS\" \/>\n<meta property=\"og:description\" content=\"Principio activo: Pazopanib Presentaciones: 400 mg x 60 comprimidos 200mg x 90 comprimidos   Mecanismo de acci\u00f3n y blancos moleculares (biol\u00f3gicos) Pazopanib inhibidor multi-tirosin quinasa de: receptores VEGD 1, 2 y 3; receptores PDGF, receptor de citoquina cKit, receptor de IL-2 inducible por quinasa de c\u00e9lulas T (Itk). Su funci\u00f3n principal es intervenir con la angiog\u00e9nesis, impidiendo el crecimiento tumoral y su sobrevida. Indicaciones terap\u00e9uticas C\u00e1ncer de c\u00e9lulas renal avanzado. Ciertas formas de sarcoma tisular de tejidos blandos. Aprobaciones y pautas (FDA; EMA; ASCO; ESMO) Paznopanib ha sido aprobado por EMA y FDA para las indicaciones anteriormente mencionadas. ASCO y ESMO recomiendan el uso de Pazopanib como tratamiento de primera l\u00ednea para pacientes con c\u00e1ncer de las c\u00e9lulas renales. Dosis y plan terap\u00e9utico El plan terap\u00e9utico var\u00eda seg\u00fan la indicaci\u00f3n. Se recomienda una dosis diaria m\u00e1xima de 800mg. La reducci\u00f3n inicial de dosis debe ser de 400mg. Aumentos o reducciones posteriores deben hacerse de a 200mg dependiendo de la tolerancia. 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